Cancer: Soft Tissue Sarcoma
Consortium: International Soft Tissue Sarcoma Consortium (INSTRuCT)
Headquarters: University of Chicago
Consortium Manager: Suzi Birz, sbirz@bsd.uchicago.edu

Researchers created this consortium with the goal of establishing a a soft tissue sarcoma data commons to share and provide access to digital objects, focusing on RMS and NRSTS clinical trials data from the United States and Europe. The INSTRuCT database integrates clinical data from the Children’s Oncology Group (COG), The European Paediatric Soft Tissue Sarcoma Study Group (EpSSG), Cooperative Weichteilsarkom Studiengruppe (CWS) der Gesellschaft für Pädiatrische Onkologie und Hämatologie (GPOH), International Society for Pediatric Oncology (SIOP) Malignant Mesenchymal Tumour (MMT), and the Italian Associazione Italiana di Ematologia e Oncologia Pediatrica (AIEOP) Soft Tissue Sarcoma Committee (STSC). You may self-register for an account to perform cohort discovery on the data in the INSTRuCT data commons.

The INSTRuCT Executive Committee has formed six discipline work groups to advance the consortium’s efforts. These efforts have resulted in the RMS and NRSTS data dictionaries and published consensus papers.  The work groups are Imaging, Pathology/Biology, Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS), Radiation Oncology, Statistics/Informatics, and Surgeons.

Information for Researchers

Cohort Discovery Tool: Log in to the PCDC Data Portal

Data Dictionaries:
Rhabdomyosarcoma Data Dictionary
NRSTS Data Dictionary

Project Requests:
Project Proposal Form
Publication Policy

See all past and ongoing INSTRuCT research projects here.

Research Contact: If you are looking for a research project or if you have a research project that you are interested in conducting with INSTRuCT data, or if you have any questions, please contact Suzi Birz at sbirz@bsd.uchicago.edu.

Data Contributors

Executive Committee

NameGroupCountry
Doug HawkinsCOGUSA
Dave RodebergCOGUSA
Suzanne WoldenCOGUSA
Wei XueCOGUSA
Ewa KoscielniakCWSGermany
Martin EbingerCWSGermany
Monika Sparber-SauerCWSGermany
Gianni BisognoEpSSGItaly
Hans MerksEpSSGNetherlands
Veronique Minard-ColinEpSSGFrance
Gian Luca De SalvoEpSSGItaly
Sam VolchenboumPCDCUSA

Bolded names indicate Executive Committee co-chairs.